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Cancer Treatments

1. Which drugs are used to treat non-small cell lung cancer and are EGF receptor inhibitors, that act as tyrosine kinase inhibitors?
Dabrafenib %26 Vemurafenib, Sonidegib, Vismodegib, %26 Cyclopamine, Afatinib, Erlotinib, %26 Gefitinib, Ruxolitinib %26 Tofacitinib
2. language Which drug inhibits RAS? It%27s a farnesyltransferase inhibitor. It%27s used to treat unresectable or metastatic melanoma with BRAF V600E or V600K mutations.
Tofacitinib, Trametinib, Palbociclib, Lonafarnib
3. Which drugs inhibit Raf? They%27re used to treat unresectable or metastatic melanoma with BRAF V600E or V600K mutations.
Dabrafenib %26 Vemurafenib, Ruxolitinib %26 Tofacitinib, Cetuximab %26 Panitumumab, Bevacizumab %26 Ziv-aflibercept
4. online learning games Which drug inhibits MEK? It%27s a dual-specificity kinase: can phosphrylate serines and tyrosines. Used to treat unresectable or metastatic melanoma with BRAF mutations
Erlotinib online activities , Trametinib, Vismodegib, Dabrafenib
5. What are small molecule inhibitors of the Jak-Stat pathway? They are used to treat myelofibrosis.
Doxorubicin %26 Dactinomycin, Sonidegib %26 Cyclopamine, Paclitaxel %26 Docetaxel, Ruxolitinib %26 Tofacitinib
6. Which one of the following is NOT a small molecule inhibitor of SMO (SHH pathway)? The drugs that are used to treat advanced basal cell carcinoma.
Sonidegib, Vismodegib, Palbociclib, Cyclopamine
7. Which drug inhibits Cdk4/6 (which normally pushes the cell into S phase) and is used to treat metastatic breast cancer?
Dabrafenib teacher , Palbociclib, Trametinib, Imatinib
8. Which are the small molecule inhibitors of BCR-ABL (tyrosine kinase inhibitors) that treat Philadelphia chromosome-positive leukemias like CML?
Cetuximab %26 Panitumumab, Ruxolitinib %26 Tofacitinib, Imatinib %26 Dasatinib, Dabrafenib %26 Vemurafenib
9. Which is an antibody inhibitor of HER2 that works by blocking HER2 receptor dimerization and is used to treat HER2 positive breast cancer?
Trastuzumab, Cetuximab, Bevacizumab, Panitumumab
10. Which drugs bind to EGFR receptors and block their dimerization? They are used to treat squamous cell carcinoma of head/neck %26 metastatic colorectal cancer.
Imatinib %26 Dasatinib, Bevacizumab %26 Ziv-aflibercept, Dabrafenib %26 Vemurafenib, Cetuximab %26 Panitumumab
11. What binds to VEGF molecules %26 sequesters them so they can%27t interact with surface VEGF receptors (prevents angiogensis)? They treat metastatic forms of cancer.
Cetuximab %26 Panitumumab, Rituximab web tool , Bevacizumab %26 Ziv-aflibercept, Sonidegib, Vismodegib, %26 Cyclopamine
12. Which antibodies induce cell death by binding to CD20 on the B cell surface and mediating their destruction by NK cells? They treat B cell non-Hodgkin lymphoma.
Cetuximab, Rituximab, Palbociclib, Lonafarnib
13. Which mitotic inhibitors are vinca alkaloids that bind to free tubulin dimers to prevent MT polymerization? They treat breast, lung, myelomas, lymphomas, and leukemias?
Paclitaxel %26 Docetaxel, Methotrexate %26 Fluorouracil (5-FU), Vincristine %26 Vinblastine, Doxorubicin %26 Dactinomycin
14. Which drugs are anti-metabolites that prevent synthesis of thymidine and thus keep the cell from replicating? They treat leukemias, breast, ovarian, and GI cancers.
Dabrafenib %26 Vemurafenib, Doxorubicin %26 Dactinomycin, Paclitaxel %26 Docetaxel, Methotrexate %26 Fluorouracil (5-FU)
15. Which DNA damaging agents work by inhibiting topoisomerase and intercalating into the DNA? They can also damage normal cells - can induce others (leukemia)
Doxorubicin %26 Dactinomycin, Paclitaxel %26 Docetaxel, Ruxolitinib %26 Tofacitinib, Imatinib %26 Dasatinib
16. Which drugs are cancer immunotherapy monoclonal antibodies that work as checkpoint inhibitors, targeting molecules working to suppress the immune system?
Cetuximab %26 Panitumumab, Ipilipmumab %26 Nivolumab, Bevacizumab %26 Ziv-aflibercept, Imatinib %26 Dasatinib