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Rectal and vaginal preparations

1. Technological disadvantages of Butyrum Cacao with its low hydroxyl number ????
low chemical stability, large melting and solidifying range, does not allow hand rolling and shaping, low coefficient of volume contraction,
2. Hydroxyl number of lipophilic supp bases gives info for
allows hand rolling and shaping, does not have meta-stable polymorphic forms, low melting and solidifying range school , an otimal coefficient of volume contraction,
3. What is the correct order of steps for preparation of supp mixed disperse system
small volume contraction coefficient, low microbiological stability assess performance , allows hand rolling and shaping quiz , incompatibility with drugs electrolytes salts of heavy metals,
4. Displacement value f is
low coefficient of volume contraction, hygroscopicity, high reactivity learning , high melting point,
5. Correction factor (k) is
semi suynthetic glycerides, triglycerides of saturated and unsaturated fatty acids, mono, di, and triglycerides of saturated fatty acids, hydrogenated oils,
6. The mass of globules should be
Low chemical stability, Unstable crystalline modifications, Low emulsification ability, low coefficient of volume contraction,
7. Which supp base will you choose if you need to include a water solution of drug like Sol.Adrenalini 0,1%25
Presence of triglycerides of unsaturated fatty acids, the lack of mono and diglycerides, its low hydroxyl number, its soft consistency,
8. Cocoa butter consists of
emulsification ability, solidification interval matching excercise , mechanical strength, tolerability,
9. Suppositories with lipophilic base should desigrate for
lipophilic supp bases, hydrophilic supp bases, all supp bases, all bases for pessaries,
10. What causes low chemical stability of cocoa butter
low chemical stability, low emulsification ability, small melting and solidification range, large coefficient of volume contraction,
11. How inclusion of air can be prevented during preparation of supp with coca butter by moulding
from 1 to 4 g, from 1 to 15g, from 1 to 10g, from 1 to 5 g,
12. Adeps solidus are
when cocoa butter is used, when PEG base is used, when hydrophilic base is used, When hydrophobic base is used,
13. Control parameters of supp according to EurPh
A number of parts - by 1 part 1 weight of the drug, A number of parts - by 1 part 1 weight of the base, Relative density of lipophilic supp base divided by...., Mass of the lipohilic supp base divided by...,
14. Low chemical stability of Oleum Cacao is due to
A number of parts - by 1 part 1 weight of the drug, A number of parts - by 1 part 1 weight of the base, Relative density of lipophilic supp base divided by...., Mass of the lipohilic supp base divided by...,
15. Use of which supp bases do not require lubrication on mould before pouring a melt
less than 30 min, more than 30 min, less than 60 min, more than 60 min,
16. Which supp bases recommends use of preservatives
less than 30 min, more than 30 min, less than 60 min, more than 60 min,
17. When is necessary to introduce a correction factor (k) when calculating a quantity of supp base
less than 30 min, more than 30 min, less than 60 min, more than 60 min,
18. Suppositories according to Eur Ph
Difficulty to take out supp from the mould, Absence of emulsification abillity, non uniform distributiuon of drugs in suppositories tool for teachers , obtaining meta stable modifications,
19. High chemical stability of Adeps Solidus is due to
by escaping vigorous stirring, by replacing cocoa buffer with another base, by vigorous stiring, by lubricating the mould with liquid paraffin,
20. Technological disavantages characterize Butyrum Cacao as suppository base
Witepsol H15, glycerinated gelatin base quiz , Witepsol W35, Oleum Cacao,
21. Which of the following statements for pessaries are true
first suspennd solid insoluble drugs in the base..., first dissolve soluble drugs then emulsify the liquid insoluble , first dissolve soluble drugs then suspend insoluble solids, keep the order of decreasing physical stability,
22. control parameters of pessaries
Supp mass to be stirred while moulding, supp mass not to be stirred while moulding, the temp of supp mass to be as lowest as possible, the temp of supp mass to be as highest as possible,
23. Disadvantages of PEG basis for suppositories
uniformity of mass, disintegration, organoleptic control, mechanical strength,
24. Classifications of rectal preparations according Ph Eur is
uniformity of mass, disintegration, organoleptic control, mechanical strength,
25. Disadvantages for glycerinated gelatin suppository base
Triglycerides of saturated and unsaturated fatty acids, mono,di,ttriglycerides of saturated fatty acids, mono and triglycerides of saturated and unsaturated fatty acids, triglycerides only of saturated fatty acids,
26. Melting interval is one of the characteristics of
Oleum Cacao, Adeps solidus, PEG bases , Glycerinated gelatin base,
27. Which supp bases allows hand rolling and shaping
Oleum Cacao, Adeps solidus, PEG bases , Glycerinated gelatin base,
28. Suppositories with lhydrophobic base should desigrate for
Lipophilic supp bases, hydrophilic supp bases, if they are dissolved in a hydrophilic base, if they are suspended in a lipophilic base,
29. Technological advantages of Adeps solidus as suppository base
Trans vaginal absorption is undesirable, Trans vaginal absorption is desirable save time , Vaginal route is intended for slowly releasing..., Vaginal route is intended for rapidly releasing...,
30. Pessaries according to Eur Ph
Polymorphic forms, mono and diglycerides, saturated fatty acids, unsaturated fatty acids,
31. Hydroxyl number of Adeps solidus characterizes the content of
solid single dose preparations...., solid multi dose preparations...., intended for vaginal administration, Exert local or systemic effect,
32. To ensure sufficient uniformity of dose in preparation of supp is necessary
Solid single dose preparations..., solid multi dose preparations...., intended for vaginal administration, Exert local or systemic effect,
33. Control parameters for suppositories according to Eur Ph are
presence of only triglycerides, presence of mono,di,triglycerides teaching , presence of glycerides of saturated fatty acids, presence of glycerides of unsaturated fatty acids,
34. Disadvantages of cocoa butter as base for suppositories
presence of only triglycerides, presence of mono,di,triglycerides, presence of glycerides of saturated fatty acids, presence of glycerides of unsaturated fatty acids,
35. Water soluble drugs release easier from
Deliverable mass, appearence, dissolution, uniformity of dosage units,
36. Vaginal tablets must desigrate for
Witepsol H15, PEG basis, Oleum Cacao crossword maker , Glycerinated gelatine base,
37. Use of which supp bases require lubrication on mould before pouring a melt
Witepsol H15, PEG basis online education , Oleum Cacao, Glycerinated gelatine base,